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About growth factor

Growth factors are a group of cytokines, containing members like Transforming Growth Factor β-1 (TGFβ-1), Insulin-like Growth Factor I (IGF-I), Bone Morphogenic Protein 2 (BMP-2), Bone Morphogenic Protein 7 (BMP-7), and Fibroblastic Growth Factor 2 (FGF-2). TGFβ and IGF-I have been shown to stimulate the production of proteoglycans (anabolic). Additionally, IGF-I has been shown to increase chondrocyte proliferation (mitogenic).

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